中华老年心脑血管病杂志

[1] Gotoh M,Miyamoto Y,Ikeshima-kataoka H.Astrocytic neuroimmunological roles interacting with microglial cells in neurodegenerative diseases[J].Int J Mol Sci,2023,24(2):1599.DOI:10.3390/ijms24021599.

[2] Yong VW.Microglia in multiple sclerosis:protectors turn destroyers[J].Neuron,2022,110(21):3534-3548.DOI:10.1016/j.neuron.2022.06.023.

[3] Kong C,Yang EJ,Shin J,et al.Enhanced delivery of a low dose of aducanumab via FUS in 5×FAD mice,an AD model[J].Transl Neurodegener,2022,11(1):57.DOI:10.1186/s40035-022-00333-x.

[4] Flury A,Aljayousi L,Park HJ,et al.A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion[J].Neuron,2025,113(4):554-571.e14.DOI:10.1016/j.neuron.2024.11.018.

[5] McAlpine CS,Park J,Griciuc A,et al.Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease[J].Nature,2021,595(7869):701-706.DOI:10.1038/s41586-021-03734-6.

[6] Edison P.Astroglial activation:current concepts and future directions[J].Alzheimers Dement,2024,20(4):3034-3053.DOI:10.1002/alz.13678.

[7] Endo F,Kasai A,Soto JS,et al.Molecular basis of astrocyte diversity and morphology across the CNS in health and disease[J].Science,2022,378(6619):eadc9020.DOI:10.1126/science.adc9020.

[8] Depp C,Sun T,Sawmita AO,et al.Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease[J].Nature,2023,618(7964):349-357.DOI:10.1038/s41586-023-06120-6.

[9] Kaya T,Mattugini N,Liu L,et al.CD8(+) T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging[J].Nat Neurosci,2022,25(11):1446-1457.DOI:10.1038/s41593-022-01183-6.

[10] Msthys H,Peng Z,Boix CA,et al.Single-cell atlas reveals correlates of high cognitive function,dementia,and resilience to Alzheimer's disease pathology[J].Cell,2023,186(20):4365-4385.e27.DOI:10.1016/j.cell.2023.08.039.

[11] Twarowski B,Herbet M.Inflammatory processes in Alzheimer's disease-pathomechanism,diagnosis and treatment:a review[J].Int J Mol Sci,2023,24(7):6518.DOI:10.3390/ijms24076518.

[12] Grubman A,Choo XY,Chew G,et al.Transcriptional signature in microglia associated with Aβ plaque phagocytosis[J].Nat Commun,2021,12(1):3015.DOI:10.1038/s41467-021-23111-1.

[13] Zhang Y,Chu JMT,Wong GTC.Cerebral glutamate regulation and receptor changes in perioperative neuroinflammation and cognitive dysfunction[J].Biomolecules,2022,12(4):597.DOI:10.3390/biom12040597.

[14] Qiu Q,LI C,Zhao X,et al.Farnesylthiosalicylic acid through inhibition of galectin-3 improves neuroinflammation in Alzheimer disease via multiple pathways[J].CNS Neurosci Ther,2024,30(11):e70127.DOI:10.1111/cns.70127.

[15] Merighi S,Nigro M,Travagli A,et al.A(2A) Adenosine receptor:a possible therapeutic target for Alzheimer's disease by regulating NLRP3 inflammasome activity?[J].Int J Mol Sci,2022,23(9):5056.DOI:10.3390/ijms23095056.

[16] Liu J,Wang Z,Liang W,et al.Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer's disease[J].Immunity,2025,58(7):1830-1846.e7.DOI:10.1016/j.immuni.2025.04.018.

[17] Lubben N,Brynildsen JK,Webb CM,et al.LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression[J].Transl Neurodegener,2024,13(1):13.DOI:10.1186/s40035-024-00403-2.

[18] Fritze J,Muralidharan C,Stamp E,et al.Microglia undergo disease-associated transcriptional activation and CX3C motif chemokine receptor 1 expression regulates neurogenesis in the aged brain[J].Dev Neurobiol,2024,84(3):128-141.DOI:10.1002/dneu.22939.

[19] Chidambaram H,Das R,Chinnathambi S.Interaction of Tau with the chemokine receptor,CX3CR1 and its effect on microglial activation,migration and proliferation[J].Cell Biosci,2020,10:109.DOI:10.1186/s13578-020-00474-4.

[20] Tillmon H,Soteros BM,Shen L,et al.Complement and microglia activation mediate stress-induced synapse loss in layer 2/3 of the medial prefrontal cortex in male mice[J].Nat Commun,2024,15(1):9803.DOI:10.1038/s41467-024-54007-5.

[21] Sanford SAI,Mcewan WA.Type-I interferons in Alzheimer's disease and other tauopathies[J].Front Cell Neurosci,2022,16:949340.DOI:10.3389/fncel.2022.949340.

[22] Chai YL,Lee JH,Chong JR,et al.Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias[J].J Neuroinflamm,2023,20(1):111.DOI:10.1186/s12974-023-02789-8.

[23] Dejanovic B,Wu T,Tsai MC,et al.Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models[J].Nat Aging,2022,2(9):837-850.DOI:10.1038/s43587-022-00281-1.

[24] Rudkowski K,Waszczuk K,Tyburski E,et al.Complement activation products in patients with chronic schizophrenia[J].J Clin Med,2023,12(4):1577.DOI:10.3390/jcm12041577.

[25] Merighi S,Nigro M,Travagli A,et al.Microglia and Alzheimer's disease[J].Mech Ageing Dev,2022,23(21):12990.DOI:10.3390/ijms232112990.

[26] 栗文静，白艳杰，王岩，等.M2小胶质细胞外囊泡在缺血性脑卒中作用中的研究进展[J].中华老年心脑血管病杂志，2024,26(6):725-728.DOI:10.3969/j.issn.1009-0126.2024.06.029

[27] Paudel YN,Angelopoulou E,Piperi C,et al.Impact of HMGB1,RAGE,and TLR4 in Alzheimer's disease (AD):from risk factors to therapeutic targeting[J].Cells,2020,9(2):383.DOI:10.3390/cells9020383.

[28] Verkhratsky A,Butt A,Li B,et al.Astrocytes in human central nervous system diseases:a frontier for new therapies[J].Signal Transduct Target Ther,2023,8(1):396.DOI:10.1038/s41392-023-01628-9.

[29] Vainchtein ID,Molofsky AV.Astrocytes and microglia:in sickness and in health[J].Trends Neurosci,2020,43(3):144-154.DOI:10.1016/j.tins.2020.01.003.

[30] Yang K,Lv Z,Zhao W,et al.The potential of natural products to inhibit abnormal aggregation of α-synuclein in the treatment of Parkinson's disease[J].Front Pharmacol,2024,15:1468850.DOI:10.3389/fphar.2024.1

[31] Fu L,Jiang G,Weng H,et al.Cerebrovascular miRNAs correlate with the clearance of Aβ through perivascular route in younger 3xTg-AD mice[J].Brain Pathol,2020,30(1):92-105.DOI:10.1111/bpa.12759.

[32] Yue Q,Leng X,Xie N,et al.Endothelial dysfunctions in blood-brain barrier breakdown in Alzheimer's disease:from mechanisms to potential therapies[J].CNS Neurosci Ther,2024,30(11):e70079.DOI:10.1111/cns.70079.

[33] Huang Y,Happonen KE,Burrola PG,et al.Microglia use TAM receptors to detect and engulf amyloid β plaques[J].Nat Immunol,2021,22(5):586-594.DOI:10.1038/s41590-021-00913-5.

[34] Hu J,Chen Q,Zhu H,et al.Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease[J].Neuron,2023,111(1):15-29.e8.DOI:10.1016/j.neuron.2022.10.021.

[35] Deng Q,Wu C,Parker E,et al.Microglia and astrocytes in Alzheimer's disease:significance and summary of recent advances[J].Aging Dis,2024,15(4):1537-1564.DOI:10.14336/ad.2023.0907.

[36] Heinrich MA,Huynh NT,Heinrich L,et al.Understanding glioblastoma stromal barriers against NK cell attack using tri-culture 3D spheroid model[J].Heliyon,2024,10(3):e24808.DOI:10.1016/j.heliyon.2024.e24808.